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User-friendly application to perform population genetics analysis GenoDive is a user-friendly application to perform population genetics analysis. It features an intuitive and clutter-free user-interface, behind which lie powerful statistical tools. GenoDive can handle genetic data as well as distance matrices and ecological data, enabling you to combine data from several different sources into a single analysis. GenoDive features several analyzes that are not available in other programs such as AMOVA-based k-means clustering, tests for clonal reproduction and AMOVA's for polyploid data, and standardized coefficients of population differentiation.And, best of all, GenoDive works on a Mac!Here are some key features of "GenoDive":· Many different types of inferences:GenoDive features many different types of statistical inferences, some of which are not available in any other population genetics software. Included inferences are among others: a flexible Analysis of Molecular Variance, estimation of standardised coefficients of population differentiation, k-means clustering of populations using a simulated annealing approach, assigning genotypic identity (clones) to individuals, testing for clonal reproduction, testing Hardy-Weinberg equilibrium, calculation of the hybrid index for individuals, and different types of Mantel tests. · Analyse multiple datasets... simultaneously!All Macs that are sold nowadays contain multiple processor cores. However, most programs are able to use only a part of the power of these new computers as they employ only a single processor at a time. GenoDive automatically detects the number of processors present in the computer and divides lengthy tasks over them all. Calculations always take place in the background, so you can perform other analyses while waiting for the results of a more lengthy analysis. · Multiple data formats:GenoDive can handle three different types of data: markerdata (e.g. from microsatellites), distance matrices (e.g. pairwise genetic distances between populations), and generic other data (e.g. the coordinates of populations), which can be combined in the statistical inferences. Importing data into GenoDive is easy: just open a file and GenoDive will automatically determine what type of data it is and will load the data into memory. GenoDive will even detect whether markerdata is in GenoDive, Fstat, Genepop, Spagedi, Genetix, BayesAss, Structure, or Migrate format. · Easily include and exclude observations:Most real-life datasets are far from perfect, some loci may be more difficult to score than others and there will always be individuals whose DNA-extraction yielded low quality DNA. In most programs this means quitting the program, editing the inputfile and then restarting the program again with the new file. GenoDive makes it easy to include or exclude loci, individuals, clones, ploidy levels, populations, or even whole groups of populations, so the effect of those outliers on the outcome of the analyses can be assessed. · A clear view over your data:GenoDive has a clear, uncluttered, interface that makes it easier for you to keep an overview of your data and analyses. You can choose between viewing your data as plain text or viewing it as a matrix. The Inspector panel shows the most important information for the current data: how many individuals are included per population, the number of populations groups, which loci are included, the number of alleles per locus and a log with the analyses that have been performed on this dataset. · Extensive Search Options:With GenoDive you can search your data in different ways: by allele, by individual name, by population, by clone, or by all those categories at the same time. The search can be very specific: you can for example search all population names that begin with the string "NL" or all alleles that are longer than 150 bp.NOTE: This is a public preliminary version which nmeans that the app still contains bugs, and some analyses are not yet fully implemented. If you use this beta-version, you are bound by honour to report any issues, bugs or praise that you may have to the author. What's New in This Release: · Improved compatibility with Mac OS 10.6 "Snow Leopard". · Removed possibility to show splash screen at startup, as this could lead to crashes. · Fixed bug in reading of GenePop format. · Internal restructuring of assignment procedures.

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